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A comprehensive study of drugs and their effects on living systems, including the mechanisms of action, therapeutic uses, adverse effects, and interactions.
Which immunomodulator agents induce more rapid bone marrow recovery after suppression by chemotherapy?
Which of the following is a sign and symptoms of tardive dyskinesia:
Client receiving antineoplastic medication should initiate bleeding precautions if:
In inserting rectal suppositories, the nurse should assist the client to a left lateral or left Sims’ position, with the upper leg flexed.
14. The drug specific target usually a protein located on the surface of a cell membrane or within
Monitor for neurotoxicity with vincristine sulfate manifested as:
Adrenergic agonist is contraindicated in clients with:
When a drug is absorbed from the GI tract, it enters the portal circulation before entering the systemic circulation.
Give the rationale of the following nursing intervention for clients receiving medications for respiratory system. 2 points each.
Benzodiazepines interact with other CNS medications, producing an additive effect. TRUE
Magnesium sulfate is contraindicated in clients with myocardial damage.
A concentrated form of a drug made from vegetables or animals.
Cardiac glycoside is used in clients with cardiogenic shock.
Digoxin (Lanoxicaps, Lanoxin) is contraindicated in clients with:
Pneumococcal conjugate vaccine (PCV) administration route is:
Antigout medication should be used cautiously in clients with gastrointestinal disease.
17. Tablet held between cheek and gum until dissolved.
Which of the following blood levels that needs to be monitored if the client is receiving Heparin sodium:
_____________10. Coal tar can stain the skin and hair.
Glucocorticoids are administered with caution in clients who have inflammatory respiratory conditions.
The process by which metabolites and drugs are eliminated from the body.
PENTAVALENT VACCINE 3.
Which of the following is not included in atropine toxicity.
11. Type of metabolites that has a pharmacologic action.
When administering levodopa, instruct the client to avoid excessive vitamin B12 intake.
Instruct the client about the need for contraception.
Promote a fluid intake of at least 2000 mL/ day.
Unexpected or unique response.
MMR vaccine administration route is:
Which of the following is not a rapid acting insulin:
When administering phenytoin intravenously, infuse no faster than 25 to 50 mg/min; otherwise, hypertension and cardiac dysrhythmias could occur.
21. Injected in tissue just below skin.
MMR vaccine protects against measles, mumps, and rubella.
Oder people who are taking sedatives require higher dosage due to decrease absorption of the drugs.
Atypical new generation medication decreases effects of dopamine serotonin and/or norepinephrine at neural membranes.
Monitor kidney and liver function studies.
Furosemide (Lasix) is a:
Replaces body fluids or substances.
20. Solution injected into intravascular compartment via a vein.
Opioids analgesics is used for:
An example of calcium channel blockers.
Physician orders 1500 mg of liquid ibuprofen for a patient. Quantity of Ibuprofen is 500 mg in 1 cc, how much will you administer?
If gold toxicity occurs, the doctor may prescribe dimercaprol (BAL in oil) to prevent gold excretion.
13. The time after administration when the body initially responds to the drug.
Transmucosal-buccal nitrates, the client should be instructed to:
Rectal route is considered topical application.
The following drug is used for moderate and severe dementia and Alzheimer’s disease.
Aluminum hydroxide is used to treat hypophosphatemia.
Supports body function until other treatments or the body’s response can take over.
Leukotriene modifiers should be used with caution in clients with impaired hepatic function.
Immunomodulators stimulates the immune system to recognize cancer cells and take action to eliminate or destroy them.
When a medication is intended for the trachea, bronchi, and/or lungs, it is inhaled through the nose.
The onset of drug action in transdermal route is slower than oral route.
Metered-dose inhaler (MDI) is a handheld nebulizer that can be used by the client to release the medication through a mouthpiece.
2. The name under which a drug is listed in one of the official publications.
6. The rate and extent to which an administered drug reaches the systemic circulation.
A flat, round, or oval preparation that dissolves and releases a drug when held in the mouth.
Tricyclic antidepressant clomipramine (Anafranil) may be used to treat obsessive- compulsive disorder.
Monitor for petechiae, ecchymosis, bleeding of the gums, and nosebleeds.
Bethanechol chloride is give only by:
Client taking prednisone should monitor glucose and serum potassium levels because it can cause hyperglycemia and hypokalemia.
______________7. Client who use Aminolevulinic acid (Levulan Kerastick) should protect the area from sunlight and bright indoor lights.
Magnesium sulfate is used with caution in clients with:
1. Order: Client is receiving Erythromycin 750 mg, the stock on hand is 250 mg in 5 mL. How many ML should be given. (5 POINTS)
22. An aerosol generator that converts liquid drug solutions or suspensions into aerosol and is powered by compressed air, oxygen, a compressor, or an electrically powered device.
A preparation like an ointment, but thicker and stiff, that penetrates the skin less than an ointment.
Antitussives should not be administered to the client with a head injury or a postoperative cranial surgery client.
Returns the body to health.
Hypersensitive, life-threatening reaction.
Due to immaturity of liver and kidney function in older client, it may lead to accumulation of the drug in the body.
Streptokinase
Client receiving Nifedipine (Procardia, Adalat, Nifedical) should avoid use or use cautiously with magnesium sulfate, to prevent which of the following?
25. Which of the following is nonbenzodiazepine anxiolytic:
Phenytoin (Dilantin) is used to treat partial and generalized tonic-clonic seizures.
The best route in allergy testing and tuberculosis screening is intradermal route.
In irrigation of the ear, the doctor may prescribe hydrogen peroxide solution.
The client receiving a laxative need to increase fluid intake.
7. If magnesium sulfate is used for preeclampsia, it may be prescribed:
Severe side effect or toxicity.
Clients receiving tocolytics should be positioned on her side.
Acetaminophen
Clients with asthma can use mucolytic agents to increase airway resistance.
An example of alpha adrenergic blockers.
Which of the following is not included in estrogen hormonal medications?
The antidote for hypertensive crisis in client taking MAOIs, is:
Spironolactone (Aldactone) is a:
Skeletal muscle relaxant is indicated for clients with cerebral palsy.
Children receiving the Varicella vaccine should avoid aspirin or aspirin-containing products.
Common complaint of clients taking an ACE inhibitor.
9. Which of the following is not an indication of prostaglandin?
Dopamine decreases the myocardial contractility thus, improving cardiac performance.
The client receiving antineoplastic medication is instructed to use a soft toothbrush and electric razor to:
Cimetidine (Tagamet) passes the blood-brain barrier.
______________8. Diclofenac sodium (Solaraze) is used in conjunction with blue light photoactivation in treating actinic keratosis.
Pneumococcal conjugate vaccine (PCV) is given orally.
Toxicity of alpha-adrenergic blockers is treated with:
Silver sulfadiazine (Silvadene, Thermazene, SSD Cream) systemic effects include leukopenia and interstitial nephritis.
BIRTH 1.
Pilocarpine
Which of the following is not correct in magnesium sulfate?
Vaccines administered intramuscularly in infants are best given in:
19. Which of the following is an indication of anticholinergic medication.
Cholinergic drug include Bethanechol chloride (Urecholine).
3. Tocolytics is used for:
The therapeutic drug serum level of lithium is:
Client taking isoniazid should be instructed to monitor for tingling, numbness, or burning of the extremities because these are signs of hepatotoxicity.
Mydriatics are contraindicated in clients with glaucoma because of the risk of decreased intraocular pressure.
Which of the following is not a short acting insulin:
Nasal decongestant can be use in client with allergic rhinitis and acute coryza.
In client taking glucocorticoids, the nurse should use this medication with extreme caution in clients with infections.
Sympathomimetic medication is used to treat hypertension, heart failure and cardiac arrest.
Offer sips of water before giving sublingual nitrates:
The nurse should instruct the client not to use sodium osmotic with older adults or children.
Thyroid hormones control the metabolic rate of tissues and decreases heat production and oxygen consumption of the body.
Bethanechol chloride (Urecholine)
Instruct the client taking amiodarone to use sunscreen and protective clothing.
During the administration of positive inotropic and cardiotonic medications, the nurse should:
Instruct the client that cyclophosphamide, when prescribed orally, is:
Which of the following blood levels that needs to be monitored if the client is receiving Warfarin sodium (Coumadin):
Give the rationale of the following nursing intervention for clients receiving medications for musculoskeletal system. 2 points each.
Topical glucocorticoids cannot be absorbed into the systemic circulation.
Immunosuppressants suppresses the immune response and alter antibody formations.
Give the rationale of the following nursing intervention for clients receiving medications for cardiovascular system. 2 points each.
Dexamethasone (Maxidex) should not be used for eye abrasions and wounds.
Glucocorticoids is intended for acute respiratory attacks.
The nurse should advise the client taking anticholinergic medication that antacid:
Instruct clients with diabetes mellitus using β-adrenergic blockers as an eye medication to monitor blood glucose levels frequently.
When receiving positive inotropic and cardiotonic medications, the nurse should monitor for?
Clients taking loop diuretics should be advised to:
Cisplatin (Platinol-AQ) may cause:
Clients receiving translingual nitrates (spray), the client should be instructed to:
Early signs of digoxin toxicity present as:
An acne product where it decreases androgen activity resulting in decrease production of sebum.
______________2. Acneiform eruptions is included also in systemic adverse effects of topical glucocorticoids.
Circadian and sleep cycles can also affect drug therapy.
Which immunomodulator slows tumor cell division?
Toxicities and overdose by the oral route may be overcome with antidotes, such as activated charcoal.
A medication mixed with alcohol, oil, or soapy emollient and applied to the skin.
When doing subcutaneous injection, the nurse should use z-track technique to avoid injecting the blood vessels.
Nitrates are contraindicated in clients with:
Aspirin should be discontinued 3 to 7 days before surgery.
In administering heparin injection, the nurse should massage the site of injection to hasten drug absorption.
Vastus lateralis muscle is the recommended site of intramuscular injection in young adult.
Parasiticidal prevents worm growth and reproduction (for pinworms).
Client taking anticholinergic has drug interaction in the following except:
Famotidine (Pepcid) and nizatidine (Axid) can be administered with food.
May be carried out indefinitely until an order is written to cancel it.
16. Which of the following is not included in client teaching in medication administration?
Take anticonvulsants with food or milk but avoid alcohol.
Benzodiazepines are contraindicated in clients with anxiety.
PENTAVALENT VACCINE 4.
Immunosuppressants used for the following except?
An aqueous solution of sugar often used to disguise unpleasant-tasting drugs.
Monitor liver function tests when a client is taking a skeletal muscle relaxant because neurotoxicity can occur.
3. This name describes the constituents of the drug precisely.
When using a bronchodilator inhalant in addition to the steroid inhalant, use the steroid at least 5 minutes prior to the bronchodilator.
This site should be avoided when injecting vaccine in intramuscular route:
CNS depressants have a calming effect on children with attention-deficit hyperactivity disorder and increase alertness and sensitivity to stimuli.
The main side effect of thrombolytic medication is formation of thrombus.
Adrenergic agonist is for:
Positive inotropic and cardiotonic medications are used for:
Nitrofurantoin is contraindicated in clients with renal impairment.
Which of the following is a sign and symptoms of Akathisia:
Which of the following prevents conversion of HIV RNA into HIV DNA?
Varicella vaccine protects against:
Psychological/physiological need to take a medication.
______________5. Sunscreen should be reapplied every 30 minutes for increase protection.
Topical eye anesthetics are used for anesthesia for eye examinations and surgery or to keep foreign bodies from the eye.
In nasal medication, the client is advised to blow their noses after the administration of nasal sprays.
Instruct the client taking anxiolytic medication to avoid alcohol and sedatives because:
1 1/2 TO 3 1/2 8.
Obtain a drug history before the administration of an opioid analgesic.
The nurse should advise the client taking cholinergic medication to take the medication as prescribe.
Administer analgesic as prescribed to client’s receiving ergot alkaloids.
Clients taking anticoagulants should not take aspirin or NSAIDS.
10. Placement of drug under the tongue.
Leukotriene increases bronchoconstriction caused by antigen and reduce airway edema.
Before administering a bolus, the nurse should look up the maximum concentration recommended for the particular drug.
Penicillins and cephalosporins should be given separately with aminoglycosides.
Topical applications includes dermatologic preparations, installations and irrigations.
Instruct the client taking fluoxetine (Prozac) or bupropion (Wellbutrin) to take the medication early in the day.
8. Most drug metabolites are eliminated in the:
______________6. In using sunscreens, products containing PABA need to be used by individuals allergic to benzocaine, sulfonamides, or thiazides.
Requiring increase dose to achieve therapeutic effect.
One of the fetal contraindications of tocolytics is the gestational age greater than 37 weeks.
Mineralocorticoids are used for primary and secondary adrenal sufficiency in Addison’s disease.
A gelatinous container to hold a drug in powder, liquid, or oil form.
Ergot alkaloids is contraindicated in clients with the following except:
In client taking oral contraceptives, advise the client to use an alternate method of birth control when taking antibiotics.
1 1/2 TO 3/12 MONTH 6.
______________3. Organic (chemical) sunscreens absorb UV light.
Fluorouracil (Adrucil) may cause alopecia, stomatitis, diarrhea, phototoxicity reactions, and cerebellar dysfunction.
Eye lubricant add moisture to the eyes.
The nurse should administer which medication in clients who developed anaphylactic reaction due to antineoplastic medications?
NSAIDs medication is included in antigout medication.
Prostaglandin is administered orally to induce labor.
The client with HIV or AIDS is at high risk for the development of:
5. The time interval required for the body’s elimination processes to reduce the concentration of the drug in the body by one-half.
For clients receiving tricyclic medications should be instructed to avoid alcohol and nonprescription medications.
Give the rationale of the following nursing intervention for clients receiving medications for urinary system. 2 points each.
Medication used to treat psoriasis that is contraindicated during pregnancy.
Client’s positive and negative expectations can increase or decrease response of the drug.
Which of the following is not a typical cholinergic effect:
Antitumor antibiotic medication, pulmonary toxicity can occur with:
Cardiac glycosides produce a negative chronotropic action, which:
Meperidine hydrochloride (Demerol) and hydromorphone hydrochloride (Dilaudid) should not administered in early labor.
7. Which of the following factors influencing absorption is not included?
Sodium nitroprusside should protect from light.
Methenamine is recommended for acute urinary tract infection.
Thrombolytic medication is contraindicated in clients with active internal bleeding.
Lithium has teratogenic effect during 3rd trimester.
Administer antiemetics several hours before chemotherapy and for 12 to 48 hours after as prescribed.
Client receiving magnesium sulfate intravenously, the nurse should call the health care provider if respirations are less than 12 breaths/min.
A licensed health professional who prepares, dispenses and advises on medicinal drugs.
______________4. Keratolytics suppresses DNA synthesis, miotic activity, and cell proliferation.
Inform the client using eye gel to store the gel at room temperature or in the refrigerator.
Transdermal patch is applied to a hairless, clean area of skin that is subject to excessive movement or wrinkling.
If the client receiving immunosuppressants, flowers, plants, fresh fruit, and raw vegetables should be discouraged.
Glucocorticoids should be used with caution in clients with diabetes mellitus.
High doses of oxytocin may cause hypotension, with:
Which of the following is a sign and symptoms of Parkinsonism:
For clients who are taking selective serotonin reuptake inhibitors (SSRI) should be administer with a snack or meal.
Mannitol (Osmitrol) is a:
For clients taking MAOI, avoid administering the medication in the evening.
Anticoagulant is contraindication in clients with myocardial infarction and deep vein thrombosis.
Prolonged use of antibiotics can increase the client’s risk of superinfections, or secondary infections.
Vaccines administered intramuscularly for children 36 months and older are best given in:
Which of the following symptoms of anaphylactic reaction due to antineoplastic medications.
Mexiletine may be administered with food or antacids.
Leukotriene modifiers are contraindicated in breast feeding mothers.
In using sunscreens, products containing PABA need to be avoided by individuals allergic to benzocaine, sulfonamides, or thiazides.
Client who are taking medication through sublingual route should be advised to keep the medication under the tongue until it is absorbed.
An example of beta adrenergic blockers.
Thiazide and thiazide-like diuretics should be used with caution in client:
When applying eye drops, the nurse should instruct the client to apply pressure over the inner canthus next to the nose for 30 to 60 seconds following administration of the medication.
15. The pharmacologic effects when the drug produces the same type of response as the physiological or endogenous substance.
Enoxaparin
Bethanechol chloride (Urecholine) is not given to a client who has a urinary stricture or obstruction.
Tincture of opium can be diluted with 15 to 30 mL of water for administration.
Which of the following is not a positive symptom of schizophrenia:
5. A scientist that researches new drugs.
Instruct the client taking lithium (Lithobid) to maintain a fluid intake of six to eight glasses of water a day and an adequate salt intake.
RhoGAM should be administered within 72 hours before potential or actual exposure to Rh-positive blood.
Prostaglandin is used for:
Dilates the pupils of the eye.
An antineoplastic medication that affect cells in any phase of the reproductive cycle.
Benzodiazepines should administer at no more than 5 mg/min intravenously to prevent bradycardia.
Magnesium sulfate
Nursing intervention necessary for client receiving mafenide acetate (Sulfamylon) include:
______________9. High-dose of anthralin (Dritho-Scalp, Psoriatec) may cause hypercalcemia.
1. Assigned by the United States Adopted Names (USAN) Council and is used throughout the drug’s lifetime.
Diazepam (Valium) acts on the CNS to suppress spasticity and affect skeletal muscle directly.
Magnesium sulfate is used for:
Also known as one-time order is for medication to be given once at a specified time.
______________1. Growth retardation is one of the systemic adverse effects of topical glucocorticoids.
TRUE OR FALSE
Medication used to treat psoriasis that is contraindicated in clients with human immunodeficiency virus infection.
Acetaminophen (Tylenol) is used to decrease pain and fever.
Skeletal muscle relaxant is contraindicated in clients with multiple sclerosis and brain attack.
If diarrhea is a problem, avoid hot foods and high-fiber foods.
Edrophonium (Tensilon)
Clients taking bronchodilators, instruct the client to administer oral medication:
Sulfonamides is contraindicated in children younger than 2 years.
Busulfan (Myleran, Busulfex) may cause:
Nursing intervention necessary for client receiving silver sulfadiazine (Silvadene, Thermazene,
Instruct the client taking a corticosteroid not to stop the medication abruptly.
The effects urinary tract antiseptics can also be use for infections outside the urinary tract.
Which of the following is benzodiazepine antagonist:
Alpha adrenergic blocker should be taken with food or milk.
9. It is a maintained concentration of a drug in the plasma during a series of scheduled doses.
Which of the following is not used to decrease extrapyramidal side effects:
4. Specialist who often guides the primary care provider in prescribing drugs.
Tamoxifen citrate may cause impotence and gynecomastia in men.
19. These routes have the highest bioavailability and not subject to first-pass metabolism or harsh GI environment.
Dr. B. orders a liter of D5W to run this 8-hour shift. The drop factor is 15. What is the drip rate per minute?
3 1/2 MONTH 7.
Mydriatics are should not be given in clients with glaucoma.
Sustained-released nitrates, the client should be instructed to:
Antihistamine is used for colds and rhinitis.
The side effects of antineoplastic medication results from its effects in cancer cells.
Buspirone effect takes 3-6 weeks, which is shorter than other anxiolytics.
Cures a disease or condition.
Hepatitis A vaccine (HepA) administration route is:
Client receiving antineoplastic medication should avoid aspirin-containing products.
Cardiac glycosides
Neuromuscular blockers is used with anesthetics during surgery to maintain muscle relaxation.
Which of the following is not a withdrawal symptom of benzodiazepine:
The dosage of a benzodiazepine should be tapered gradually over:
12. Type of metabolites that does not have pharmacologic action.
The nurse should administer adrenergic agonist through a large vein.
If the client decides to discontinue the contraceptive to become pregnant, recommend that the client use an alternative form of birth control for 2 months after discontinuation.
Metabolites is the product of biotransformation.
Give the antidote of the following medications. 2 points each.
Client taking alpha adrenergic blocker should be instructed to change positions slowly.
An antineoplastic medication that affect cells only during a certain phase of the reproductive cycle.
Inappropriate intake of a medication.
Bronchodilators are indicated in clients with emphysema and other restrictive airway disease.
Opioid antagonist used to treat respiratory depression from opioid overdose.
4. It is the metabolic conversion of drug molecules to more water-soluble metabolites or less active form that are more readily excreted.
Antidiuretic hormones enhances reabsorption of water in the kidneys.
Which of the following is a sign and symptoms of dystonia:
Abrupt withdrawal of adrenergic blockers may lead to:
Varicella vaccine administration route is:
Neuromuscular blockers
Enteric coated medication can be crush and mix with food if the client has difficulty swallowing.
Antineoplastic medication causes the slow destruction of cells, resulting in the release of uric acid.
The physician orders 500 mg of ibuprofen for a patient and you have 250 mg on hand. How many tablets should be given? ( 5PTS)
Which of the following damages HIV’s DNA interfering with ability control host DNA?
Clients receiving antiemetic should protect from injury.
Antigout medications can increase desired effect by taking aspirin.
II. Enumeration Give at least five rights in medication administration.
Montelukast, oral (Singulair) should be taken 1 hour before or 2 hours after meal.
Theophylline is a glucocorticoid medication.
Client taking antigout medication should be instructed to avoid foods high in purine.
9 MONTHS TO 1 YEAR 9.
Antithyroid medication is used for hyperthyroidism or Grave’s disease.
Opioid analgesic
Sodium bicarbonate may cause milk-alkali syndrome.
Antitumor antibiotic medication, dysrhythmias can occur with:
Osmotic medication is used for emergency treatment of glaucoma.
Cardiac glycosides produce a positive inotropic action, which:
BIRTH 2.
PENTAVALENT VACCINE 5.
Anticholinergic medication is also known as cholinergic-blocking agents.
Bile acid sequestrants should use cautiously in clients with suspected bowel obstruction or severe constipation.
Phenytoin decreases the effectiveness of some birth control pills and can have teratogenic effects if taken during pregnancy.
Parasympatholytic medication is used in children and clients with narrow-angle glaucoma.
In administering eye medication, instruct the client to read the medication labels carefully.
Placement under the tongue allows a drug to diffuse into the capillary network and to enter the systemic circulations indirectly.
Hepatotoxic medications are avoided with the use of androgens.
The vaccines should be stored on a center shelf and not on the door.
Tocolytics produce uterine relaxation and suppress uterine activity.
Antacids is used in clients with peptic ulcer disease and gastroesophageal reflux disease.
18. Best route in administering drugs that are poorly absorbed from the GI tract and for agents that are unstable in GI tract.
Typical antipsychotic medication is given in clients exhibiting alogia.
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