Triple-Negative Breast Cancer

Which of the following is a risk factor for developing TNBC?

• A family history of breast cancer.
• High intake of fatty foods.
• Regular physical activity.
• Having children at an older age.

What is the role of radiation therapy in TNBC treatment?

• It is used after surgery to kill any remaining cancer cells.
• It is the first line of treatment.
• It is used as the sole treatment.
• It is used to shrink the tumor before surgery.

What is a common challenge in treating TNBC?

• Hormone therapy resistance.
• Lack of targeted therapies.
• Presence of HER2 receptors.
• Tumor cells being estrogen-sensitive.

Which receptor is absent in TNBC tumors?

• Estrogen, progesterone, and HER2 receptors.
• Estrogen receptors only.
• Progesterone receptors only.
• HER2 receptors only.

How do doctors classify TNBC in terms of its aggressiveness?

• It is classified as a high-grade cancer.
• It is classified as low-grade.
• It is classified as benign.
• It is classified as moderate-grade.

Which ethnic group has a higher prevalence of TNBC?

• Caucasian women.
• African American women.
• Asian women.
• Hispanic women.

What is the most important factor for determining treatment for TNBC?

• The stage of cancer at diagnosis.
• Patient age.
• The size of the tumor alone.
• Whether the tumor is malignant or benign.

What does "BRCA-positive" mean in the context of TNBC?

• It means the cancer is linked to a hereditary gene mutation.
• It means the cancer responds well to chemotherapy.
• It means the tumor is estrogen-sensitive.
• It means the tumor is slow-growing.

Which medication is NOT used to treat TNBC?

• Tamoxifen (used for hormone-positive cancers).
• Doxorubicin.
• Paclitaxel.
• Carboplatin.

What role does chemotherapy play in the treatment of TNBC?

• It helps kill fast-growing cancer cells.
• It prevents the growth of estrogen receptors.
• It repairs DNA damage in the tumor cells.
• It stimulates the immune system to target the cancer.

What is a common treatment for Triple-Negative Breast Cancer?

What is the likelihood of recurrence for TNBC after initial treatment?

• TNBC has a higher likelihood of recurrence within the first few years.
• TNBC has a low recurrence rate.
• Recurrence happens only after 10 years.
• There is no risk of recurrence.

What is the survival rate for patients diagnosed with TNBC compared to other types of breast cancer?

• It has a lower survival rate.
• It has the same survival rate.
• It has a higher survival rate.
• The survival rate is still being studied.

How is TNBC typically diagnosed?

• Mammography and biopsy.
• Mammography, ultrasound, and biopsy.
• PET scan and MRI.
• Blood test and ultrasound.

What is the most effective treatment combination for TNBC?

• Chemotherapy followed by surgery and radiation.
• Monoclonal antibody treatment.
• Hormonal therapy followed by radiation.
• Surgery alone.

Which protein is often missing in TNBC cells?

• HER2 protein.
• EGFR protein.
• Estrogen receptors.
• Progesterone receptors.

What is one reason why TNBC is harder to treat?

• It is less responsive to chemotherapy.
• It does not respond to hormone therapies.
• It is less likely to spread to lymph nodes.
• It tends to be found in smaller tumors.

What lifestyle factor is associated with a lower risk of TNBC?

• Regular exercise and a healthy diet.
• Maintaining a healthy weight.
• Smoking cessation.
• Avoiding hormonal treatments.

What is the standard surgical procedure for TNBC?

• Mastectomy or lumpectomy, depending on tumor size.
• Lymph node dissection only.
• Only radiation therapy.
• Chemo-induced tumor removal.

What is a major barrier to TNBC treatment?

• Lack of targeted therapies for this subtype.
• High cost of surgery.
• Resistance to chemotherapy.
• Overexpression of estrogen receptors.

What is the main method of screening for breast cancer, including TNBC?

• Mammography.
• MRI.
• CT scan.
• Biopsy.

Which age group is most commonly diagnosed with TNBC?

• Women under the age of 40.
• Women over the age of 60.
• Women in their 30s and 40s.
• Women over 70 years old.

Which type of breast cancer has a better prognosis compared to TNBC?

• Hormone receptor-positive breast cancer.
• TNBC is the most treatable form of breast cancer.
• HER2-positive breast cancer.
• Metastatic breast cancer.

How is the HER2 gene related to TNBC?

• It is overexpressed in TNBC cells.
• It is not overexpressed in TNBC cells.
• It makes TNBC cells more resistant to chemotherapy.
• It helps tumors metastasize more quickly.

What is the role of immune therapy in TNBC treatment?

• It may be used in some cases to stimulate the immune system to target cancer cells.
• It is used to reduce tumor size before surgery.
• It has no role in TNBC treatment.
• It is used to treat only hormone-positive cancers.

Which treatment is NOT effective for TNBC?

• Hormonal therapy.
• Hormonal therapy is ineffective for TNBC.
• Chemotherapy.
• Surgery.

Which of the following genetic mutations is associated with TNBC?

• BRCA1 mutation.
• BRCA2 mutation.
• EGFR mutation.
• p53 mutation.

What is a recent advancement in the treatment of TNBC?

• Immunotherapy and targeted therapies.
• Only surgery and chemotherapy.
• Hormonal treatment options.
• Increased radiation options.

What is the most common chemotherapy drug used for TNBC?

• Doxorubicin.
• Tamoxifen.
• Herceptin.
• Sunitinib.

Which of the following is true about the spread of TNBC?

• It can spread quickly to other organs, such as the lungs or liver.
• It typically remains localized in the breast.
• It only spreads to nearby lymph nodes.
• It spreads mainly to the bones.

What is Triple-Negative Breast Cancer (TNBC)?

• A subtype of breast cancer that lacks estrogen, progesterone, and HER2 receptors.
• A type of breast cancer that is estrogen positive.
• A form of cancer that involves only the lymphatic system.
• A rare type of tumor that forms in the brain.

Which of the following is a characteristic feature of TNBC?

• It does not express estrogen receptors, progesterone receptors, or HER2.
• It is slow-growing and easy to treat.
• It has high expression of estrogen and progesterone receptors.
• It tends to be diagnosed at later stages.

How is TNBC typically classified in staging?

• Staging is based on tumor size, lymph node involvement, and metastasis.
• It is classified only based on tumor size.
• It is staged only based on genetic mutations.
• It is not staged.

What is the prognosis for patients diagnosed with TNBC compared to other types of breast cancer?

• TNBC generally has a poorer prognosis.
• TNBC has the same prognosis as estrogen-positive breast cancer.
• TNBC patients tend to have better outcomes.
• TNBC has a better prognosis due to better treatment options.

What is the key to successful treatment of TNBC?

• Early detection and aggressive treatment.
• Targeted therapy for HER2.
• Hormonal therapy for estrogen-positive patients.
• Delayed surgery after chemotherapy.

What is one reason why TNBC is referred to as a "difficult" cancer to treat?

• It does not respond to hormonal therapies like other types of breast cancer.
• It grows slowly and can be easily managed.
• It only affects older women.
• It is always treatable with chemotherapy.

What does the term "negative" refer to in Triple-Negative Breast Cancer?

• The absence of three receptors: estrogen, progesterone, and HER2.
• The tumor is benign.
• It is a term for non-invasive cancers.
• The absence of lymph node involvement.

What is one reason why TNBC has a poorer prognosis?

• It does not respond to hormonal treatments.
• It is less aggressive than other cancers.
• It can be treated with surgery alone.
• It has a higher survival rate.

How does the growth rate of TNBC compare to other forms of breast cancer?

• TNBC tends to grow more quickly.
• TNBC grows slowly and is easier to treat.
• TNBC has the same growth rate as estrogen-positive tumors.
• TNBC is less aggressive than other types.

Which factor can increase the likelihood of a better outcome for TNBC?

• Early detection and treatment.
• Lack of symptoms.
• Hereditary mutations.
• Presence of estrogen receptors.

Which of the following is NOT a symptom of TNBC?

• A lump in the breast.
• A fever that does not subside.
• Pain in the breast or underarm.
• Skin changes in the breast.

What genetic test may be performed to evaluate the risk of TNBC?

• BRCA genetic testing.
• CTC analysis.
• Proteomic testing.
• Colonoscopy.

What type of therapy is most commonly used to treat TNBC?

• Chemotherapy.
• Hormone therapy.
• Immunotherapy.
• Radiation therapy.